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Acasa >> Editorial >> Bolile cardiovasculare la femeile aflate in perimenopauza


Bolile cardiovasculare la femeile aflate in perimenopauza

Majoritatea femeilor se tem de cancerul de sin. Acesta este responsabil doar pentru 3% din decesele femeilor , afectiunile cardiovasculare sunt raspunzatoare de moartea a 55% dintre femei pe tot teritoriul Europei. Si in Romania aceste proportii se respecta oarecum , fara a avea insa date foarte exacte.
Tipic , femeile sunt cu 10 ani mai batrine decit barbatii , cind dezvolta o boala cardiovasculara. Totusi, desi inaitea virstei de 45-54 ani, evenimentele cardiovasculare sunt rare la femei, dupa aceasta virsta, numarul lor creste semnificativ.
Una din explicatiile diferentei intre frecventa bolilor cardiovasculare la femeile si barbatii de virste tinere , consta in efectele cardioprotective ale estrogenilor endogeni.
Scaderea rapida a nivelelor de estrogen plasmatic explica modificarile nefavorabile ale metabolismului lipidelor si glucidelor care apar in perioada de peri si imediat post menopauza.
Asa incit dupa menopauza se constata la femei :
  • crestrea sedentarismului
  • cresterea in greutate, mai ales la femeile care nu primesc terapie de substituie hormonala;
  • cresterea valorilor tensiunii arteriale sistolice si diastolice;'
  • aparitia unui grad de depresie;
  • apartia unui grad de disfunctie sexuala.
Se poate spune ca aparitia menopauzei duce la un grad de afectare a calitatii vietii si cresterea incidentei afectiunilor cardiovasculare. Una din solutii este terapia de substitutie hormonala. Decizia unei astfel de terapii trebuie luata cu sprijinul medicului specialist cardiolog si ginecolog, punind in balanta de fiecare data, riscul versus beneficiul terapiei.Cardiovascular

Diseases at Peri-Menopausal Women


Most of women have a great fear of breast cancer , but this is responsible for only about 3% of total deaths, despite of cardiovascular diseases which are responsible for about 55 % all women's deaths all across Europe. This ratio is valid for Romania , but we don't have very exact data.
Typically , women are with 10 years older than men when they develop cardiovascular diseases. Before 45-54 years older, cardiovascular events are rare at women. But , after that age the cardiovascular events' number increase significant.
Endogenous estrogen are responsible for cardioprotective mechanism at young women.
Dramatically decreased of plasma estrogen levels in women at peri and post menopause explain unfavorable lipid and carbohydrate metabolism changes.
Women at menopause are characterized by:
  • incresing level of sedentary;
  • weight gain ( mainly at women who not received hormone replacement therapy);
  • increasing the systolic and diastolic blood pressure;
  • depression;
  • sexual dysfunction;
Over all we can say that menopause negative influence the quality of life and the increasing incidence of cardiovascular diseases. One solution can be hormone replacement therapy. This decision must be made by the cardiologist and gynecologist , according with benefits versus therapy 's risks.

Management of cardiovascular risk in the peri- menopausal women : a consensus statement of European cardiologists and gynecologists, European Heart Journal(2007)28,2028-2040